Search on: PLATELET DERIVED GROWTH FACTOR RECEPTOR 
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Descriptor English:   Receptors, Platelet-Derived Growth Factor 
Descriptor Spanish:   Receptores del Factor de Crecimiento Derivado de Plaquetas 
Descriptor Portuguese:   Receptores do Fator de Crescimento Derivado de Plaquetas 
Synonyms English:   PDGF Receptor
Platelet-Derived Growth Factor Receptor
Platelet Derived Growth Factor Receptor
Platelet Derived Growth Factor Receptors
Receptor, PDGF
Receptors, Platelet Derived Growth Factor
Platelet-Derived Growth Factor Receptors
PDGF Receptors
Receptors, PDGF  
Tree Number:   D08.811.913.696.620.682.725.400.900
D12.776.543.750.630.625
D12.776.543.750.750.400.630
Definition English:   Specific receptors on cell membranes that react with PLATELET-DERIVED GROWTH FACTOR, its analogs, or antagonists. The alpha PDGF receptor (RECEPTOR, PLATELET-DERIVED GROWTH FACTOR ALPHA) and the beta PDGF receptor (RECEPTOR, PLATELET-DERIVED GROWTH FACTOR BETA) are the two principle types of PDGF receptors. Activation of the protein-tyrosine kinase activity of the receptors occurs by ligand-induced dimerization or heterodimerization of PDGF receptor types. 
Indexing Annotation English:   DF: RECEPT PDGF
See Related English:   Platelet-Derived Growth Factor
 
History Note English:   93; was PLATELET-DERIVED GROWTH FACTOR RECEPTOR (NM) 1982-92; PLATELET DERIVED GROWTH FACTOR RECEPTOR-KINASE was NM 1989-92 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   30547 
Unique Identifier:   D017479 

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